Service offer of Intana Bioscience  

Intana Bioscience offers interaction analysis of biomolecular interaction based on a single molecule sensitive spectroscopic approach called fluorescence cross-correlation spectroscopy (FCCS).

Advantages of FCCS

FCCS has many advantages, e.g.:
  • It allows measurements in physiological environments (e.g. cell lysates, serum, intra-ocular fluids), circumventing purification steps
  • It offers a comprehensive readout (KD, kon/off, diffusion coefficients, non-specific binding, aggregation, etc.)
  • It is a generic technology (applicable to proteins, peptides, DNA/RNA, small molecules, etc.)
  • It enables label-free determination of affinities and kinetics
  • Its dynamic range is suitable for most physiologically-relevant interactions (pico- to micromolar range)
  •  It requires very little amounts (ng quantities)

Meet us on June 13th to 16th in Boston at the 5th NovAliX Conference
Biophysics in Drug Discovery 2018

See our new publication on the quantifiaction of target occupancy in tissue:

Check out our new GPCR-ligand interaction assay!