Human kinase profiling platform  


We established a kinase profiling platform with 520 human kinase domains. This platform allows examining inhibitor potency and specificity in cellular lysates, providing an advantage over readily-available biochemical solutions.
1. We offer a complete scan of the kinome (520 KD values), provided the compound to test can be labeled with a fluorophore. Kinetics are also feasible. Please contact us to discuss your needs.

2. Alternatively, we offer readily-available assays for 288 kinase domains, enabling KI determination of label-free test compounds. Kinetics are also feasible. Please contact us to discuss your needs.


Meet us on November 13th to 16th in Dublin at the 30th EORTC-NCI Conference on Molecular Targets and Cancer Therapeutics.

See our new publication on the quantifiaction of target occupancy in tissue:
https://doi.org/10.18632/oncotarget.22801

Check out our new GPCR-ligand interaction assay!