Full-length RTK assay  


Our established biochemical assays enable measuring of affinities and kinetics of label-free ligand-RTK interaction. The assays leverage carefully optimized solubilization conditions that allow production of monodisperse RTK particles. Available for EGFR, Her2, Her3, FLT4, PDGFRb, EphB2, FGFR1 and C-MET. Please contact us for a quote. 


We recently published with our customer Merck KGaA the use of FCCS to support the identification of Methionine Aminopeptidase-2 (MetAP-2) inhibitor M8891.
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01070


See our new publication on the quantifiaction of target occupancy in tissue:
https://doi.org/10.18632/oncotarget.22801


Check out our new GPCR-ligand interaction assay!